Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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2,341
Tocris Bioscience™ SW 033291
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation
| Target | Dehydrogenase Inhibitors |
|---|---|
| CAS | 459147-39-8 |
| Purity | >98% |
| Chemical Name or Material | 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H20N2OS3 |
| Formula Weight | 412.59 |
2,342
Tocris Bioscience™ CU CPT 22
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CAS: 1416324-85-0 Molecular Formula: C19H22O7
| CAS | 1416324-85-0 |
|---|---|
| Molecular Formula | C19H22O7 |
2,343
Tocris Bioscience™ Vinblastine sulfate
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CAS: 143-67-9 Molecular Formula: C46H60N4O13S
| CAS | 143-67-9 |
|---|---|
| Molecular Formula | C46H60N4O13S |
2,344
Tocris Bioscience™ Batimastat
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CAS: 130370-60-4 Molecular Formula: C23H31N3O4S2
| CAS | 130370-60-4 |
|---|---|
| Molecular Formula | C23H31N3O4S2 |
2,345
Tocris Bioscience™ CGP 37157
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CAS: 75450-34-9 Molecular Formula: C15H11Cl2NOS
| CAS | 75450-34-9 |
|---|---|
| Molecular Formula | C15H11Cl2NOS |
2,346
Tocris Bioscience™ AZD 9272
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Potent and selective mGlu5 antagonist; brain penetrant
| Target | Group I mGluR Antagonists |
|---|---|
| CAS | 327056-26-8 |
| Purity | >98% |
| Chemical Name or Material | 3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile |
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C14H6F2N4O |
| Formula Weight | 284.22 |
2,347
Tocris Bioscience™ CASIN
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Cdc42 inhibitor
| Product Type | CASIN |
|---|---|
| Molecular Weight (g/mol) | 306.4 |
| Purity | >98% |
2,348
Tocris Bioscience™ Ceritinib
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Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at 4°C |
| Synonym | LDK378 |
| Molecular Formula | C28H36ClN5O3S |
| Formula Weight | 558.14 |
2,349
Tocris Bioscience™ Neurodazine
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Induces neurogenesis in mature skeletal muscle cells
| Inhibitors | Neurodazine |
|---|---|
| Product Type | Neurodazine |
| Molecular Weight (g/mol) | 456.92 |
| Purity | >99% |
2,350
Tocris Bioscience™ BIBN 4096
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Potent and selective CGRP antagonist
2,351
Tocris Bioscience™ OXA 06 dihydrochloride
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Potent ROCK inhibitor
| Inhibitors | OXA 06 dihydrochloride |
|---|---|
| CAS | 1825455-91-1 |
| Product Type | OXA 06 dihydrochloride |
| Molecular Weight (g/mol) | 404.31 |
| Purity | >98% |
2,352
Tocris Bioscience™ PHA 665752
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CAS: 477575-56-7 Molecular Formula: C32H34Cl2N4O4S
| CAS | 477575-56-7 |
|---|---|
| Molecular Formula | C32H34Cl2N4O4S |
2,353
Tocris Bioscience™ Thioridazine hydrochloride
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CAS: 130-61-0 Molecular Formula: C21H27ClN2S2
| CAS | 130-61-0 |
|---|---|
| Molecular Formula | C21H27ClN2S2 |
2,354
Tocris Bioscience™ PF 05175157
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Acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor
| Target | Additional Lipid Metabolism Compounds |
|---|---|
| CAS | 1301214-47-0 |
| Purity | >98% |
| Chemical Name or Material | 1,4-Dihydro-1′-[2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4′-piperidin]-7(6H)-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C23H27N5O2 |
| Formula Weight | 405.49 |
2,355
Tocris Bioscience™ Phenyl-glutarimide 4'-oxyacetic acid
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Functionalized cereblon ligand for PROTAC development